Osteoporosis, Osteopenia, and Bone Health

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Majid Ali, M.D.

The Health and Strength of a Bone Depends Upon the Health and the Strength of the Muscles Acting upon it

 

The Dysox Model of Osteoporosis

Disrupted Signaling of the Oxygen-Insulin Matrix Signalling

T-Score and Z-Score for Bone Health

Bone density scan reports present the bone density findings under two columns designated “T- Score” and “Z-Score.” Do you know what the two terms mean? Do you know the term T Score is a shameless deception? Consider this:
1. Suppose a doctor prescribes a drug for your 74-year-old mom to increase her muscle mass. He bases his decision on a test that compared your mom’s muscle mass to that of a twenty-year-old woman. How would you react to that?
2. Next, suppose you discover that the drug blocks muscle regeneration (modeling). What would you think about the state of the mind of the doctor who prescribed that drug?
3. Next, you find that the drug prescribed for your mom has serious negative effects including increased risk of cancer. What would you think of the doctor’s ethics?
4. Next, you discover that the doctor neither recognized that his test compared the muscle mass of your mom to that of a 20-year-old nor that top medical journals have repeatedly told doctors that the drug actually injures the muscles and decreases muscle mass. What would be your state of the mind?

 

Fosamax, Actinel, and Related Blockers of Bone Regeneration (Remodeling)

A well-kept secret of Fosamax is that its extended use is associated with an increased risk of fracture. That should be obvious to anyone who knows that Fosamax blocks bone strengthening with regeneration and remodeling. Consider the following from an editorial published in the prestigious journal Clinical Endocrinology and Metabolism: “I believe the current evidence suggests that bisphosphonates should be stopped after 5 yr. Those patients who remain at a high risk of fractures or who have had fractures despite bisphosphonate therapy could be considered for treatment with intermittent PTH [parathyroid hormone]… In otherwise healthy perimenopausal women who merely have osteopenia, the best therapeutic option is not clear. “ ( J. Clin. Endocrinol. Metabolism 2005; 90(3):1897-1899.)

Health education is completely controlled by profiteers of Disease-Literacy, Drug-Literacy, and Procedure-Literacy

The central tragedy of healing arts is that health education is completely controlled by profiteers of Disease-Literacy, Drug-Literacy, and Procedure-Literacy. What people need is Healing-Literacy, which is a path of learning, understanding, and knowing health and healing. The T Score deception is just one example. Healing-Literacy about bone health (which is not possible without bone regeneration with remodeling), one truly understands the deceptive claims of the clinical uses of drugs like Fosamax, Actinel, and others that block of bone remodeling.

Please Read This Before You Take Fosamax, Boniva, and Related Drugs

Here are some questions that are to be considered before anyone takes Fosamax and related drugs used for osteoporosis.
5. Considering the information provided in the first four questions above, why do you think your mom’s doctor prescribed the drug?
6. What percentage of doctors might know the crucial difference between T-Scores and Z- Scores?
7. What are two factors in common among the following concerning the bone tissue?
A. Inflammation, including arthritis
B. Fractures
C. Microtrauma
D. Tissue microdamage
E. Smoking
F. Poor circulation
G. Mycotoxins (mold toxins)
(If you recognize excess acidity and bone loss as common to all of the above, you are right.)
8. How does oxygen preserve bone health?

As Muscles Breathe, So Do Bones

Here are the answers to the above question:
1. You would be puzzled, then wonder what the doctor was thinking. You know one needs exercise for strengthening muscles.
2. You would wonder what happened to the doctor’s common sense. You know muscle continually re-model themselves for health and strength.
3. You would be very offended that your mom’s health is being put under jeopardy because the doctor cannot think straight.
4. You would be angry to learn that your mom has been deceived.
5. The leaders of the doctor’s professional association have been paid off by drug companies. And the doctor is too lazy to learn about how the drug really works and its long-term toxicity.
6. Sensepenia is a deep deficit of common sense.
7. T- Score indicates the average strength of the bone of twenty-year-old women. Z-Score indicates the average bone strength of women of the patient’s age. Drug companies promote their drugs by pushing T-Scores—by comparing the bone density of women in sixties, seventies, eighties, and beyond with those of twenty-years-olds.
8. Regrettably, most doctors do not appreciate the crucial difference between T-Scores and Z- Scores. For this article, I asked twelve doctors to explain to me the difference between T- Scores and Z-Scores. Not one of them could do it.

Guidelines for Nutrient Support

My top priorities for bone health are high-frequency, low-intensity exercise, the bowel and liver detox, low-acid diet, and judicious use of nutrient supplementation.(1) Specifically:
1. Limbic exercise
2. Limbic Breathing
3. Castor oil rubs
4. Hydrogen peroxide soaks
5. Nutrient supplements
 

Mineral Supplementation,

it is imperative that that appropriate laboratory tests be performed for assessment.
My general guidelines include the following:
vitamin D (2,000 to 5,000 units);
vitamin K3 (0.1 to 0.3 mg);
magnesium (500 to 750 mg);
calcium (500 to 750 mg);
potassium (100 to 150 mg);
zinc (25 to 50 mg);
and selenium, chromium, and molybdenum (400 to 600 mcg each);
and small amounts of trace minerals including boron and strontium (see note at the end).
I also I recommend liberal daily doses of oxystatic and redox-restorative nutrients,
including glutathione (100-300 mg);
co-enzyme Q10 (100 to 200 mg);
MSM (methylsulfonylmethane) 750 to 1,500 mg);
taurine (750 to 1,500 mg); and antioxidant vitamins.
Vitamin D helps in the synthesis of a hormone called osteocalcin which is essential for bone calcium regulation.
Vitamin K participates in bone calcium regulation G1a (an amino acid named gamma-carboxyglutamic acid). G1a also prevents calcium deposits in blood vessels and other soft tissues.
See our related article Essential Vitamins
See reference #1 and the companion article entitled “Liver Detoxification” for detailed information about these subjects. See “Notes” below for some explanatory comments.
Optimal protein intake is crucial for bone health. See “Breakfast and Health”
For a detailed discussion of the pathophysiology of osteopenia and osteoporosis, I refer professional readers to chapter 12 entitled “The Dysox Model of Osteoporosis” in my book Darwin, Dysox, and Disease, the eleventh volume of The Principles and Practice of Integrative Medicine. (1)
References
1. Ali M. The Principles and Practice of Integrative Medicine Volume XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York. Institute of Integrative Medicine Press.
2. Tonino RP, Meunier PJ, Emkey R, Rodrigues-Portales JA, Menkes CJ, Wasnich RD, Bone HG, Santora AC, Wu M, Desai R, Ross PD. Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. J Clin Endocrinol Metab 85:3109-3115.
3. http://nyp.org/news/hospital/fosamax-fracture-risk.html
4. Odvina CV, Zerwekh JE, Sudhaker Rao D, Maalouf N, Gottschalk FA, Pak CYC. Severely suppressed bone turnover: A potential complication of alendronate therapy. J. Clin. Endocrinol. Metabolism 2005; 90(3):1294-1301.
5. Ott SM. Editorial: Long-term safety of bisphosphonates. J. Clin. Endocrinol. Metabolism 2005; 90(3):1897-1899.
6. Schneider JP. Should Bisphosphonates be Continued Indefinitely? An Unusual Fracture in a Healthy Woman on Long-Term Alendronate. Geriatrics. 2006;61:31-33.
7. Dianne Wysowski, New England Journal Medicine. 2009:360:89-90.
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