CANCER TALK FOR PROSTATE CANCER
Majid Ali, M.D.
1-C, 344 Prospect Ave, Hackensack, NJ 07601
Read the companion article entitled:
Prostate Cancer – Truths and Mistruths
Cancer Talk and Its Results
How does the conversation go during a visit with prostate cancer surgeon?
How does the conversation go during a visit with prostate cancer radiation oncologist?
How does the conversation go during a visit with a doctor for active monitoring of prostate cancer?
What is the focus of cancer during a visit with radiation oncologist yprostate cancer surgeon?
If you have local prostate cancer and are between 50 and 69, surgery will not help you, so say the British who have national health service for all citizens.
ProtecT Trial of Prostate Cancer Treatments
For learning the truths and mistruths about prostate cancer, please read, re-read, then again re-read the results of the British Protect Trial published in The New England Journal of Medicine on
October 16, 2016 .
(2016; Volume 375: pages 1415-1424.
If you do not have any biology or medical background, please get your public library to give you a print-out of the article and your doctor to read the abstract of the article, especially he Conclusion section. It will be more useful to you than any long discussion of the treatment options of prostate cancer.
Know the subject well before making your decision.
Surgery for Prostate Cancer
– Do You Need It? If so, under what conditions?
Do you need radiotherapy? If so, under what conditions?
Do you wish cancer control without surgery or radiotherapy?
If so, under what conditions?
A quote from the report
“At a median follow-up of 10 years, the ProtecT trial showed that mortality from prostate cancer was low, irrespective of treatment assignment.”
“Prostatectomy and radiotherapy were associated with lower rates of disease progression than active monitoring;” Notwithstanding, a ten-years follow-up showed no long-term benefits of surgery.
Here Is Something Else Interesting
Another quote from the article:
“Synthesizing these data, the U.S. Preventive Services Task Force recommended that population screening for prostate cancer should not be adopted as a public health policy, because risks appeared to outweigh benefits from detecting and treating PSA-detected disease.”
A total of 545 men were randomly assigned to active monitoring, 553 to radical prostatectomy, and 545 to radiotherapy. The median age of the participants was 62 years (range, 50 to 69), the median PSA level at the prostate-check clinic was 4.6 ng per milliliter (range, 3.0 to 19.9), 77% had tumors with a Gleason score of 6 (on a scale from 6 to 10, with higher scores indicating a worse prognosis), and 76% had stage T1c disease;
X. Hamdy FC, Donovan J, Lane JA, et. al. 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer.N Engl J Med 2016; 375:1415-1424
N Engl J Med 2016; 375:1415-1424October 13, 2016DOI: 10.1056/NEJMoa1606220
The ProtecT Trial
The management of clinically localized prostate cancer that is detected on the basis of prostate-specific antigen (PSA) levels remains controversial. In the United States alone, an estimated 180,890 cases will be diagnosed in 2016, and 26,120 men will die from the disease.1 The widespread use of PSA testing has resulted in a dramatic increase in the diagnosis and treatment of prostate cancer, but many men do not benefit from intervention because the disease is either indolent or disseminated at diagnosis. Prostate cancer often progresses slowly, and many men die of competing causes. In addition, interventions for prostate cancer can have adverse effects on sexual, urinary, or bowel function. Two treatment trials have evaluated the effectiveness of treatment, but they did not compare the most common contemporary methods: surgery, radiotherapy, and monitoring or surveillance.2-4
The National Institute for Health Research–supported Prostate Testing for Cancer and Treatment (ProtecT) trial recruited men 50 to 69 years of age in the United Kingdom. From 1999 to 2009, a total of 82,429 men had a PSA test; 2664 received a diagnosis of localized prostate cancer (including 146 men from the feasibility study), and 1643 agreed to undergo randomization to active monitoring, radical prostatectomy, or radiotherapy. Here we report the effectiveness of each intervention in relation to prostate-cancer–specific mortality and all-cause mortality and the incidence of metastases and disease progression at a median of 10 years of follow-up in the randomized trial. In a companion article, we report complete patient-reported outcomes in the randomized cohort at 6 years of follow-up.5
A total of 545 men were randomly assigned to active monitoring, 553 to radical prostatectomy, and 545 to radiotherapy. The median age of the participants was 62 years (range, 50 to 69), the median PSA level at the prostate-check clinic was 4.6 ng per milliliter (range, 3.0 to 19.9), 77% had tumors with a Gleason score of 6 (on a scale from 6 to 10, with higher scores indicating a worse prognosis), and 76% had stage T1c disease; there were no meaningful differences at baseline among the three randomized groups.6 Information on baseline demographic and clinical characteristics according to assigned treatment group is provided in Table S2 in the available with the full text of this article at NEJM.org.
Dr. Ali’s Library of Videos and Articles
… Cancer videos. Beware of Cholesterol Drugs Used for Prostate Cancer Majid Ali MD … Obesity Increases the Risk of Prostate Cancer by 57% Majid Ali MD …
May 28, 2014 – Majid Ali, MD discusses various treatment options for Prostate cancer in the videos below. Beware of Cholesterol Drugs Used for Prostate …
Dec 7, 2014 – A common prostate cancer therapy should not be used in men whose cancer has not spread … Prostate PIN Cancer Is Not Cancer Majid Ali MD …
May 16, 2016 – Majid Ali, M.D. At the time of diagnosis, if you panic, you won’t make it. Science, Philosophy, and Basics of Cancer Treatment Science: Cancer …
Posts about Prostate Cancer Treatment Options written by Majid Ali MD.
Course on Prostate Health. Majid Ali, M.D.. The prostate gland of a man is healthy when he does not even know he has the gland. Men first learn about its …
I explain mechanisms by which obesity increase the risk of prostate cancer. For more info, please go to www …
May 14, 2016 – Dr. Majid Ali is joined byJanet Coleman for a Science, Health and Healing Special. … Dr. Ali’s 2-DVD Breast and Prostate Cancer Package.
In this 40-minute video seminar, Professor Majid Ali, M.D. addresses the … Dr. Ali’s Course on Cancer Seminar 2 – The Oxygen Model of Cancer …. Majid Ali, M.D, discusses various treatment options and their efficacy for Prostate cancer.
Aug 11, 2008 – New recommendations about prostate cancer screening show that sometimes not knowing is … Majid Ali, M.D. August 12, 2008 · 10:57 am.
Breast Cancer Part 2 – Treatments and options by Majid Ali. M.D. … Majid Ali, M.D, discusses various treatment options and their efficacy for Prostate cancer.
Majid Ali, M.D. ** Prostate Cancer Surgery **Think Twice. No, Twenty Times ** Ali Academy. … ExploreProstate Cancer Treatment and more!
Hyperinsulinism Associated with Breast and Prostate Cancer by Majid Ali, MD. References. 1. Ali. M. Respiratory-to-Fermentative (RTF) Shift in ATP Production …