Immuno – Lyme Disorder

Majid Ali, M.D.

The So-Called Chronic Lyme Disease Is An Immune Disorder

Which Begins As A Microbial Infection


I expect sharp, possibly stinging, response to my view of the so-called chronic Lyme disease stated above. Regrettably I know of many patients who are so heavily invested in their ownership of chronic Lyme disease that they see any opposing view of the diseases as a challenge to that ownership.

The Severe Suffering of immuneo-Lyme Disorder Is Real

I am a physician and have deep empathy for all those suffer chronically with any disorder. I take the risk of offending some people in the hope that many, many more can see the reality and escape extended antibiotic therapy which deepens and prolong their misery. I have seen many people whose chronic illness following acute Lyme disease became worse with extended antibiotics therapy and have not seen people who regained health with such therapy.

The Nature of Immuno-Lyme Disorder

There are many examples of people developing a chronic immune disorder after inadequate treatment of an infectious disorder. Common examples include autoimmune hepatitis following viral hepatitis and chronic fatigue syndrome after Epstein-Bar viral infection.

My View of Immune-Lyme Disorder Is Based On the Following:

  1. None of the hundreds of patients with acute Lyme disease treated by my colleagues and I went on to develop the so-called chronic disease.
  2. None of our patients with acute Lyme disease needed to have doxycycline or other antibiotics for more than eight weeks except two who needed such therapy for 12 weeks.
  3. My colleagues and I never considered antibiotic therapy for acute Lyme disease (or any other acute infection) complete treatment.
  4. My colleagues and I considered natural immune-boosting therapies more important than antibiotic therapies.
  5. I describe our nondrug treatment plans in detail in the 10th, 11th, and 12th volumes of my 14-volume textbook entitled The Principles and Practice of Integrative Medicine. Our focus is on boosting the immune system by: (1)  bowel and liver detox with spices and herbs; (2) antiviral oxygen therapies; (3) insulin-wise food choices; (4) support for the thyroid, adrenals, and pancreas; and (5) deep healing spiritual work. My textbook is available in print and digital formats at or by calling 212-873-2444.

A Major 2016 Report Validates My View

A major 2016 study funded by  the Netherlands Organization for Health Research and Development and published in The New England Journal of Medicine completely validates my position on the matter stated above. Below is the abstract of that paper:

In patients with persistent symptoms attributed to Lyme disease, longer-term antibiotic treatment did not have additional beneficial effects on health-related quality of life beyond those with shorter-term treatment. (Funded by the Netherlands Organization for Health Research and Development. (NEJM. 2016;374:1209-1220.)

Below is some more text from the above-cited report for readers’ interest:

“Patients with Lyme disease, which is caused by the Borrelia burgdorferisensu lato complex (including B. afzelii and B. garinii in Europe), often report persistent symptoms.1 These symptoms are also referred to as the post–Lyme disease syndrome or chronic Lyme disease and may occur after resolution of an erythema migrans rash or after other — possibly unnoticed — manifestations of early Lyme disease, regardless of whether a patient received initial appropriate antibiotic treatment. Patients present mainly with pain, fatigue, and neurologic or cognitive disturbances.2,3



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